Schedule for New England Patriots for 2008 season
| Week | Opponent | Result | ||
| 1 | KC | W 17-10 | play by play | graph |
| 2 | @NYJ | W 19-10 | play by play | graph |
| 3 | MIA | L 13-38 | play by play | graph |
| 5 | @SF | W 30-21 | play by play | graph |
| 6 | @SD | L 10-30 | play by play | graph |
| 7 | DEN | W 41-7 | play by play | graph |
| 8 | STL | W 23-16 | play by play | graph |
| 9 | @IND | L 15-18 | play by play | graph |
| 10 | BUF | W 20-10 | play by play | graph |
| 11 | NYJ | L 31-34 | play by play | graph |
| 12 | @MIA | W 48-28 | play by play | graph |
| 13 | PIT | L 10-33 | play by play | graph |
| 14 | @SEA | W 24-21 | play by play | graph |
| 15 | @OAK | W 49-26 | play by play | graph |
| 16 | ARI | W 47-7 | play by play | graph |
| 17 | @BUF | W 13-0 | play by play | graph |