Schedule for Houston Texans for 2008 season
| Week | Opponent | Result | ||
| 1 | @PIT | L 17-38 | play by play | graph |
| 3 | @TEN | L 12-31 | play by play | graph |
| 4 | @JAC | L 27-30 | play by play | graph |
| 5 | IND | L 27-31 | play by play | graph |
| 6 | MIA | W 29-28 | play by play | graph |
| 7 | DET | W 28-21 | play by play | graph |
| 8 | CIN | W 35-6 | play by play | graph |
| 9 | @MIN | L 21-28 | play by play | graph |
| 10 | BLT | L 13-41 | play by play | graph |
| 11 | @IND | L 27-33 | play by play | graph |
| 12 | @CLE | W 16-6 | play by play | graph |
| 13 | JAC | W 30-17 | play by play | graph |
| 14 | @GB | W 24-21 | play by play | graph |
| 15 | TEN | W 13-12 | play by play | graph |
| 16 | @OAK | L 16-27 | play by play | graph |
| 17 | CHI | W 31-24 | play by play | graph |