Schedule for San Diego Chargers for 2006 season
| Week | Opponent | Result | ||
| 1 | @OAK | W 27-0 | play by play | graph |
| 2 | TEN | W 40-7 | play by play | graph |
| 4 | @BAL | L 13-16 | play by play | graph |
| 5 | PIT | W 23-13 | play by play | graph |
| 6 | @SF | W 48-19 | play by play | graph |
| 7 | @KC | L 27-30 | play by play | graph |
| 8 | STL | W 38-24 | play by play | graph |
| 9 | CLE | W 32-25 | play by play | graph |
| 10 | @CIN | W 49-41 | play by play | graph |
| 11 | @DEN | W 35-27 | play by play | graph |
| 12 | OAK | W 21-14 | play by play | graph |
| 13 | @BUF | W 24-21 | play by play | graph |
| 14 | DEN | W 48-20 | play by play | graph |
| 15 | KC | W 20-9 | play by play | graph |
| 16 | @SEA | W 20-17 | play by play | graph |
| 17 | ARI | W 27-20 | play by play | graph |
| (post) | NE | L 21-24 | play by play | graph |