Schedule for Pittsburgh Steelers for 2006 season
| Week | Opponent | Result | ||
| 1 | MIA | W 28-17 | play by play | graph |
| 2 | @JAC | L 0-9 | play by play | graph |
| 3 | CIN | L 20-28 | play by play | graph |
| 5 | @SD | L 13-23 | play by play | graph |
| 6 | KC | W 45-7 | play by play | graph |
| 7 | @ATL | L 38-41 | play by play | graph |
| 8 | @OAK | L 13-20 | play by play | graph |
| 9 | DEN | L 20-31 | play by play | graph |
| 10 | NO | W 38-31 | play by play | graph |
| 11 | @CLE | W 24-20 | play by play | graph |
| 12 | @BAL | L 0-27 | play by play | graph |
| 13 | TB | W 20-3 | play by play | graph |
| 14 | CLE | W 27-7 | play by play | graph |
| 15 | @CAR | W 37-3 | play by play | graph |
| 16 | BAL | L 7-31 | play by play | graph |
| 17 | @CIN | W 23-17 | play by play | graph |